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Anti-phospho-Caspase 6 (Ser257) antibody (bs-5240R)

Anti-phospho-Caspase 6 (Ser257) antibody (bs-5240R)

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Anti-phospho-Caspase 6 (Ser257) antibody

英文名称phospho-Caspase 6 (Ser257)
中文名称磷酸化半胱胺酸蛋白酶蛋白6抗体
别    名Apoptosis-related cysteine protein; Apoptosis Related Cysteine Protease; Apoptotic cysteine protease MCH2; Apoptotic protease MCH 2; Apoptotic protease MCH2; Casp 6; Casp6; Caspase 6 apoptosis related cysteine protease; Caspase 6 precursor; Caspase6; Human cysteine protease Mch2 isoform alpha; Mch 2; Mch2; CASP6_HUMAN.  

DATASHEET

Host:Rabbit

Target Protein:phospho-Caspase 6 (Ser257)

IR:Immunogen Range:KV(p-S)QR

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:839

Swiss Prot:P55212

Source:KLH conjugated synthetic peptide derived from human Caspase-6:KV(p-S)QR 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Caspase-6 is involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Subunit is compose of heterodimer of a18 kDa (p18) and a 11 kDa (p11) subunit. Subcellular location at cytoplasmic. Cleavages by CPP32, caspase-8 or -10 generate the two active subunits. It belongs to the peptidase C14 family.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti-phospho-Caspase 6 (Ser257) (bs-5240R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 11/33 kD
Observed band size: 33 kD

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