Anti-Human IgA antibody (bs-0360R)

Anti-Human IgA antibody

Quantity size:

10mg

Background:

Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B-cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA.

Also known as:

Human Immunoglobulin A; hu IgA;

Specificity:

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Rabbit Polyclonal IgG, Affinity purified by Protein A.

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Reacts with: hu.

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Immunogen: Native Human IgA.

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Predicted Molecular Weight: 170kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:1000-5000  ELISA=1:2000-10000  IHC-P=1:200-1000  IHC-F=1:200-1000  
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.