Thyroglobulin (Native) (bs-0291P)

Thyroglobulin (Native)

Quantity size:

10mg

MW:

660kDa

Source:

Natural protein

Form:

lyophilized powde

Purity:

≥95% (Purified by HPLC)

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Immunology research

Background:

Thyroglobulin from bovine thyroid
form: powder
purity: ≥90% (agarose gel electrophoresis)
mol wt: ~670 kDa
Sigma-Aldrich: T1001

? ?Bovine thyroglobulin is a large, tetrameric glycoprotein produced in the thyroid gland as a precursor to thyroid hormones. Its large size and absence from plasma under normal conditions makes it very immunogenic and reduces the chance that antibodies to this carrier protein will cross-react with plasma proteins in immunoassays. Haptens may be conjugated to thyroglobulin via accessible secondary amines.
? ?Iodine-containing protein that is stored in the thyroid gland. Converted into circulating thyroxines when the thyroid is stimulated by TSH (Thyroid Stimulating Hormone) from the pituitary. Often used as a carrier protein for the production of antibodies. Its advantage as a carrier protein comes from its large number of tyrosine residues that can be used for conjugation using the diazo reaction.

Also known as:

Thyroglobulin from bovine thyroid;

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.