CXCR6 Peptide (bs-1628P)

CXCR6 Peptide

Quantity size:

500ug

Source:

Synthetic Peptide

Form:

lyophilized powde

Purity:

≥95% (Purified by HPLC)

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Blocking Peptide of The bs-1628R Antibody

Background:

Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells. They are dependent upon an interaction between the viral envelope glycoprotein with T cell antigen T4 (CD4) and a G protein coupled receptor (GPCR). HIV1 infection relies upon interaction with a chemokine receptor, usually chemokine (C-C) receptor 5 (CCR5). During progression of the infection, the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4). SIV also utilizes CCR5 in the early stages of infection, but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15). Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes.

Also known as:

CXC-chemokine receptor 6; BONZO; C X C chemokine receptor type 6; CD 186; CD186; CD186 antigen; CDw186; Chemokine (C X C motif) receptor 6; Chemokine C X C motif receptor 6; Chemokine C-X-C Motif Receptor 6; Chemokine CXC motif receptor 6; Chemokine receptor 6; CXC chemokine receptor type 6; CXC R6; CXCR 6; CXCR6; G protein coupled receptor; G protein coupled receptor bonzo; G protein coupled receptor STRL 33; G protein coupled receptor STRL33; G protein coupled receptor TYMSTR; STRL 33; STRL33; TYMSTR.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.