CD40L Peptide (bs-1286P)

CD40L Peptide

Quantity size:

500ug

Source:

Synthetic Peptide

Form:

lyophilized powde

Purity:

≥95% (Purified by HPLC)

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Blocking Peptide of The bs-1286R Antibody

Background:

CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.

Also known as:

TNFSF5; CD 154; CD154; CD 40L; CD154; CD154 antigen; CD40 homologue; CD40 ligand; CD40LG; gp39; hCD40L; HIGM1; Hyper IgM syndrome; IGM; IMD3; Ly62; T B cell activating molecule; T cell antigen GP39; TBAM; TNF related activation protein; TNF superfamily member 5; Tnfsf5; TRAP; Tumor necrosis factor (ligand) superfamily member 5.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.