p38 MAPK/MKK3/MAPKK14 Peptide (bs-0637P)

p38 MAPK/MKK3/MAPKK14 Peptide

Quantity size:

500ug

Source:

Synthetic Peptide

Form:

lyophilized powde

Purity:

≥95% (Purified by HPLC)

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Blocking Peptide of The bs-0637R Antibody

Background:

p38 is a 38 kDa Stress Activated Protein Kinase / Map Kinase (SAPK / MAPK) that is fully activated by dual phosphorylation on threonine 180 and tyrosine 182, within the activation loop. p38 MAPK plays a critical role in the initiation of G2 delay after ultraviolet radiation; gene knock out studies have also revealed a critical role for p38 in cardiac remodeling. Downstream targets of p38 include the transcription factors ELK1 and ATF2 and the kinases MAPKAPK2 and MAPKAPK5. p38 MAPK plays a role in the production of IL6 and is thought to stabilize erythropoietin production during hypoxic stress.

Also known as:

CSBP1; CSBP2; EXIP; MAP kinase MXI2; MAP kinase p38 alpha; MAPK14; MAX interacting protein 2; K14_HUMAN; Mxi2; p38 ALPHA; p38; p38 MAP kinase; p38 MAPK; p38/MAPK; p38 mitogen activated protein kinase; p38ALPHA; p38alpha Exip; PRKM14; PRKM15; RK; SAPK 2A; SAPK2A; Stress Activated Protein Kinase 2A.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.