Osteocrin Peptide (bs-9566P)

Osteocrin Peptide

Quantity size:

100ug

MW:

5.621kDa

Sequence:

SFSGFGSPLDRLSAGSVDHKGKQRKVVDHPKRRFGIPMDRIGRNRLSNSRG-NH2

Source:

Synthetic Peptide

Form:

lyophilized powde

Purity:

≥95% (Purified by HPLC)

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Biological activity
Immunology research
Blocking Peptide of The bs-9566R Antibody

Background:

Musclin, also designated osteocrin (Ostn), shows no homology with any known genes, except that it contains two conserved sequence motifs homologous to the natriuretic peptide family. Musclin is highly expressed in cells of osteoblast lineage and in skeletal muscle tissue, where it is tightly regulated by nutritional changes. It is secreted as either a full-length precursor protein or a processed form. A novel skeletal muscle-derived secretory factor, Musclin may play a role in bone formation and be linked to glucose metabolism. Studies indicate that insulin increases Musclin expression, whereas epinephrine, isoproterenol and forskolin reduce its expression. Musclin is expressed in osteoblasts and young osteocytes. In mouse tissues, expression is bone-specific, although minimal Musclin expression is also observed in muscle, kidney, testis and heart tissues.

Also known as:

Musclin; OSTN; OSTN_HUMAN.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.