Recombinant BVDV E2 Protein (bs-20022P)

Recombinant BVDV E2 Protein

Quantity size:

100ug

MW:

45kDa

Source:

Recombinant protein

Form:

lyophilized powde

Purity:

≥95% (Purified by HPLC)

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Immunology research

Background:

Initial binding to target cell probably involves interaction of E(rns) with glycosaminoglycans. E1 and/or E2 are responsible of cell attachment with CD46 and subsequent fusion after internalization of the virion by endocytosis (Probable).
P7 forms a leader sequence to properly orient NS2 in the membrane.
Uncleaved NS2-3 is required for production of infectious virus.
NS2 protease seems to play a vital role in viral RNA replication control and in the pathogenicity of the virus.
NS3 displays three enzymatic activities: serine protease, NTPase and RNA helicase.
NS4A is a cofactor for the NS3 protease activity.
RNA-directed RNA polymerase NS5 replicates the viral (+) and (-) genome.

Also known as:

polyprotein [Bovine viral diarrhea virus 1]; POLG_BVDVN; Envelope glycoprotein E2; BVDV Envelope glycoprotein E2; PestiV1gp1 polyprotein [ Bovine viral diarrhea virus 1 ].

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.