Recombinant human Cystatin-C protein
英文名称 | Recombinant human Cystatin-C protein |
中文名称 | 重组人胱抑素C蛋白 |
别 名 | Cystatin 3; Cystatin-3; CST 3;CST3; CST-3; Cystatin C; AD 8; AD8; Amyloid angiopathy and cerebral hemorrhage; Cst 3; Cst3; CST3 protein; Cystatin 3; Cystatin3; CystatinC; Gamma trace; HCCAA; Neuroendocrine basic polypeptide; Post gamma globulin; ARMD11; MGC117328; CYSC. |
性 状 | Lyophilized or Liquid |
种属同源 | Human |
序 列 | 27-146/146aa |
产品来源 | 基因工程表达 |
分 类 | 重组蛋白 |
纯化方法 | 亲和层析 |
产品应用 | Immunology research
|
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
产品介绍 | Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin, or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family. |
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