Recombinant Streptolysin O protein
英文名称 | Recombinant Streptolysin O protein |
中文名称 | 重组链球菌溶血素O |
别 名 | SLO; Thiol-activated cytolysin; SPs0132; |
性 状 | Lyophilized or Liquid |
种属同源 | streptococcus |
序 列 | 78-571/571aa |
产品来源 | 基因工程表达 |
分 类 | 重组蛋白 |
纯化方法 | 亲和层析 |
产品应用 | Immunology research
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保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
产品介绍 | Streptolysin is a streptococcal hemolytic exotoxin. Types include streptolysin O (SLO), which is oJNCgen-labile, and streptolysin S (SLS), which is oJNCgen-stable. An antibody, antistreptolysin O, can be detected in an antistreptolysin O titre. Streptolysin O is hemolytically active only in a reversibly reduced state, unlike streptolysin S, which is stable in the presence of oJNCgen. Another difference is that SLO is antigenic, while SLS is not antigenic due to its small size. The main function of streptolysin O is to cause hemolysis (the breaking open of red blood cells) — in particular, beta-hemolysis. Increased levels of aso titre in the blood could cause damage to the heart and joints. In most cases, penicillin is used to treat patients with increased levels of aso titre. |
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