Recombinant Human TNF alpha (Active,Tag free)
| 英文名称 | Recombinant Human TNF alpha (Active,Tag free) |
| 中文名称 | 重组人肿瘤坏死因子α (活性的, Tag free) |
| 别 名 | Tumor necrosis factor-α; APC1; Cachectin; DIF; Differentiation inducing factor; Macrophage cytotoxic factor; MCF; Necrosin; TNF a ; TNF alpha; TNFalpha; TNF; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precurso; Tumour Necrosis Factor Alpha. |
| 分 子 量 | 17kDa |
| 性 状 | lyophilized powder |
| 种属同源 | human |
| 序 列 | 77-233aa, Tag free, full length mature protein |
| 产品来源 | 基因工程表达 |
| 分 类 | 细胞因子 |
| 产品应用 | Biological activity Immunology research |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
| 产品介绍 | Tumor necrosis factor alpha (TNFα) is an EGF related polypeptide growth factor that signals through the TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and also produced by monocytes, keratinocytes, and various tumor cells. TNFα stimulates the proliferation of a wide range of epidermal and epithelial cells. TNFα is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia. Under certain conditions it can stimulate cell proliferation and induce cell differentiation, impair regulatory T cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. |
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