Recombinant Human IL-28A (Active,Tag free)
| 英文名称 | Recombinant Human IL-28A (Active,Tag free) |
| 中文名称 | 重组人白介素28A (活性的, Tag free) |
| 别 名 | rhIL-28A; Interleukin 28/Interferon lambda-2; Interleukin 28A; IL28A; IFNL2; IL-28A; rhIL-28A; EG330496; Ifnl2; IFNL2_HUMAN. |
| 分 子 量 | 24kDa |
| 性 状 | lyophilized powder |
| 种属同源 | human |
| 序 列 | 26-200aa, Tag free, full length mature protein |
| 产品来源 | 基因工程表达 |
| 分 类 | 细胞因子 |
| 产品应用 | Biological activity Immunology research |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
| 产品介绍 | IL-28A, also named interferon λ2 (IFNλ2), belongs to the type III interferon protein family, which is distinct from the type I IFNs. IL-28A is induced by virus infection or double stranded RNA. IL-28A acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. IL-28A has antiviral, antitumour and immunomodulatory activities, plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. |
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