Recombinant Human IL-23 (Active,Tag free)
| 英文名称 | Recombinant Human IL-23 (Active,Tag free) |
| 中文名称 | 重组人白介素23 (活性的, Tag free) |
| 别 名 | rhIL-23; IL 23; IL 23A; IL23P19; Interleukin 23 alpha subunit p19; JKA3 induced upon T cell activation; P19; SGRF; IL-23 subunit alpha; IL-23-A; IL-23p19; IL23; Il23a; IL23A_HUMAN; Interleukin 23 p19 subunit; Interleukin-23 subunit alpha; Interleukin-23 subunit p19; JKA3 induced upon T cell activation; MGC79388; P19. |
| 分 子 量 | 55kDa |
| 性 状 | lyophilized powder |
| 种属同源 | human |
| 序 列 | 23-328aa, Tag free, full length mature protein |
| 产品来源 | 基因工程表达 |
| 分 类 | 细胞因子 |
| 产品应用 | Biological activity Immunology research |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
| 产品介绍 | IL-23 is a heterodimeric cytokine composed of two subunits: a unique p19 subunit, and a p40 subunit that is shared with IL-12. IL-23 is secreted by activated dendritic cells and macrophages. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T cells and promotes production of proinflammatory cytokines, such as IFNγ and IL-17. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
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