Recombinant Human IL-29 (Active,Tag free)
| 英文名称 | Recombinant Human IL-29 (Active,Tag free) |
| 中文名称 | 重组人白介素28B (活性的, Tag free) |
| 别 名 | Interleukin-29; rhIL-29; IL-29; IL 29; IL29; Interferon lambda-1; Cytokine ZCYTO21; IFN lambda 1; IFNL1; Interferon lambda 1; IFNL1_HUMAN. |
| 分 子 量 | 29-35kDa |
| 性 状 | lyophilized powder |
| 种属同源 | human |
| 序 列 | 20-200aa, Tag free, full length mature protein |
| 产品来源 | 基因工程表达 |
| 分 类 | 细胞因子 |
| 产品应用 | Biological activity Immunology research |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
| 产品介绍 | IL-29 belongs to the type III interferon protein family, which is distinct from the type I IFNs. IL29 is induced by virus infection or double stranded RNA. IL-29 acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. IL-29 has antiviral, antitumour and immunomodulatory activities. IL-29 is primarily active in epithelial cells and this cell type selective action is because of the epithelial cell specific expression of its receptor IFNLR1. It also exerts an immunomodulatory effect by up regulating MHC class I antigen expression. |
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