Anti-Caspase-1 P10 antibody
| 英文名称 | Caspase-1 P10 |
| 中文名称 | 天冬氨酸-胱氨酸特异性蛋白酶家族抗体 |
| 别 名 | caspase-1 isoform alpha p10 subunit; CASP 1; CASP1; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase1; ICE; IL 1 beta converting enzyme; IL 1BC; IL1B convertase; IL1BC; IL1BCE; Interleukin 1 beta convertase; Interleukin 1 beta convertase precursor; Interleukin 1 beta converting enzyme. CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; Caspase-1 subunit p10. |
DATASHEET
Host:Rabbit
Target Protein:Caspase-1 P10
IR:Immunogen Range:321-404/404
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:834
Swiss Prot:P29466
Source:KLH conjugated synthetic peptide derived from human Caspase-1 P10:321-404/404
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms. [provided by RefSeq].
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
Flow-Cyt(1μg/Test)
Cross Reactive Species:Human
Mouse
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Lung Cell (Mouse) Lysate at 40 ug
Primary: Anti-NKG2D (bs-20616R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 10/45 kD
Observed band size: 45 kD
Sample:
Raji(Human) Cell Lysate at 30 ug
Primary: Anti-Caspase-1 P10 (bs-20616R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 10/45 kD
Observed band size: 45 kD
Sample:
Liver Cell (Mouse) Lysate at 40 ug
Primary: Anti-NKG2D (bs-20616R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 10/45 kD
Observed band size: 45 kD
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