Anti-Inhibin beta B antibody
| 英文名称 | Inhibin beta B |
| 中文名称 | 抑制素βB/Inhibin β B抗体 |
| 别 名 | MGC157939; Activin A; Activin AB alpha polypeptide; Activin AB; Activin AB beta polypeptide; Activin B; Activin beta A chain; Activin beta B chain; ActivinA; ActivinAB; ActivinB; EDF; Erythroid differentiation protein; follicle stimulating hormone releasing protein; FRP; FSH releasing factor; FSH releasing protein; INHBA; INHBB; Inhibin; Inhibin beta 1; Inhibin beta 2; Inhibin beta A; Inhibin beta A chain; Inhibin beta A subunit; Inhibin beta B; Inhibin beta B chain; Inhibin beta B subunit; |
DATASHEET
Host:Rabbit
Target Protein:Inhibin beta B
IR:Immunogen Range:251-350/407
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3625
Swiss Prot:P09529
Source:KLH conjugated synthetic peptide derived from human Inhibin beta B:251-350/407
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq].
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Sheep
Guinea Pig
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Brain (Mouse) Lysate at 40 ug
Primary: Anti- Inhibin beta B (bs-1825R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 50 kD
Sample:
A431(Human) Cell Lysate at 40 ug
Primary: Anti- Inhibin beta B (bs-1825R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 50 kD
Paraformaldehyde-fixed, paraffin embedded (rat ovary tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Inhibin beta B) Polyclonal Antibody, Unconjugated (bs-1825R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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