Anti-IL17 antibody
| 英文名称 | IL17 |
| 中文名称 | 白介素-17抗体 |
| 别 名 | IL-17; IL 17; IL17; Other Aliases: Interleukin-17; CTLA 8 ; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated protein 8 ; Cytotoxic T lymphocyte associated serine esterase 8; IL 17A; IL17A; Interleukin 17; Interleukin 17A; Interleukin17; Interleukin17A; IL17_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:IL17
IR:Immunogen Range:35-130/155
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3605
Swiss Prot:Q16552
Source:KLH conjugated synthetic peptide derived from human IL-17:35-130/155
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:IL17, also known as CTLA8, is a T cell derived hematopoietic cytokine. It was originally cloned from a T cell hybridoma produced by fusion of a mouse cytotoxic T cell clone and a rat T lymphoma. IL17 exhibits multiple biological activities on a variety of cells including: the induction of IL6, IL8 and GCSF production in fibroblasts; the enhancement of surface expression of ICAM 1 in fibroblasts; activation of NF kappaB and costimulation of T cell proliferation. IL17 is an approximately 16 kDa polypeptide of 136 amino acids. The precursor form of IL17 consists of 155 amino acids. To generate the mature IL17 (136 amino acids), the precursor cleaves a 19 amino acid signal peptide. Human IL17 shows approximately 62.5% amino acid homology to mouse IL17 and 58% amino acid homology to rat IL17.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
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For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
MOLT-4(Human) Cell Lysate at 30 ug
U937(Human) Cell Lysate at 30 ug
Primary: Anti-IL17 (bs-2140R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 15 kD
Observed band size: 14 kD
Sample: Mcf-7 Cell Lysate at 30 ug
Primary: Anti- IL-17 (bs-2140R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 15 kD
Observed band size: 15 kD
Sample:
Raji(Human) Cell Lysate at 30 ug
Primary: Anti-IL17 (bs-2140R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 15 kD
Observed band size: 14 kD
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