Anti-Collagen I antibody
| 英文名称 | Collagen I |
| 中文名称 | I型胶原蛋白/胶原蛋白1/1型胶原蛋白/I型胶原a1抗体 |
| 别 名 | Collagen type I; Alpha 1 type I collagen; Alpha 2 type I collagen; COL1A1; COL1A2; Collagen I alpha 1 polypeptide; Collagen I alpha 2 polypeptide; Collagen Of Skin Tendon And Bone; Collagen Type 1; Collagen type I alpha 1; Collagen type I alpha 2; OI4; Osteogenesis Imperfecta Type IV; Pro alpha 1(I) collagen; Type I procollagen; CO1A1_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:Collagen I
IR:Immunogen Range:201-300/1464
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1277
Swiss Prot:P02452
Source:KLH conjugated synthetic peptide derived from human Collagen alpha-1(I) chain:201-300/1464
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
NIH/3T3(Mouse) Cell Lysate at 30 ug
Primary: Anti-Collagen I (bs-7158R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 95 kD
Observed band size: 125 kD
Sample:
Blood plasma (Rat) at 40 ug
Blood serum (Rat) at 40 ug
Primary: Anti-Collagen I (bs-7158R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 95 kD
Observed band size: 125 kD
Sample:
Ovary (Rat) Lysate at 40 ug
Uterus (Mouse) Lysate at 40 ug
Ovary (Mouse) Lysate at 40 ug
Primary: Anti-Collagen I (bs-7158R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 95 kD
Observed band size: 120/130 kD
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