Anti-phospho-TGF beta Receptor II (Ser225) antibody
| 英文名称 | phospho-TGF beta Receptor II (Ser225) |
| 中文名称 | 磷酸化转移生长因子β受体2抗体 |
| 别 名 | TGF beta Receptor II (phospho Ser225); p-TGF beta Receptor II (phospho S225); TGF beta Receptor II (phospho Ser225); p-TGFβ RII (Ser225); AAT3; FAA3; LDS1B; LDS2B; MFS2; RIIC; TAAD2; TbetaR II; TbetaR-II; TGF beta receptor type II; TGF beta receptor type IIB; TGF beta type II receptor; TGF-beta receptor type II; TGF-beta receptor type-2; TGF-beta type II receptor; TGFB R2; TGFbeta - RII; TGFbeta RII; TGFBR2; TGFR-2; TGFR2_HUMAN; Transforming growth factor beta receptor II; Transforming growth factor beta receptor type II; Transforming growth factor beta receptor type IIC; Transforming growth factor, beta receptor II (70/80kDa); Transforming growth factor-beta receptor type II. |
DATASHEET
Host:Rabbit
Target Protein:phospho-TGF beta Receptor II (Ser225)
IR:Immunogen Range:DR(p-S)DI
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7048
Swiss Prot:P37173
Source:KLH conjugated synthesised phosphopeptide derived from human TGF beta Receptor II around the phosphorylation site of Ser225:DR(p-S)DI
Purification:affinity purified by Protein A
Storage:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Spleen (Mouse) Lysate at 40 ug
Primary: Anti- p-TGF beta Receptor II(Ser225) (bs-20300R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 62 kD
Observed band size: 64 kD
Sample:
Lung (Mouse) Lysate at 40 ug
Primary: Anti- p-TGF beta Receptor II(Ser225) (bs-20300R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 62 kD
Observed band size: 64 kD
Sample:
Lumph node (Mouse) Lysate at 40 ug
Primary: Anti- p-TGF beta Receptor II(Ser225) (bs-20300R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 62 kD
Observed band size: 64 kD
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