Anti-TIM4 antibody
| 英文名称 | TIM4 |
| 中文名称 | T淋巴细胞膜蛋白4抗体 |
| 别 名 | SMUCKLER; Spleen, mucin-containing, knockout of lymphotoxin protein; T cell immunoglobulin and mucin domain containing protein 4; T-cell immunoglobulin and mucin domain containing 4; T-cell membrane protein 4; TIM-4; Tim4; Tim 4; TIMD 4. |
DATASHEET
Host:Rabbit
Target Protein:TIM4
IR:Immunogen Range:61-160/374
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:91937
Swiss Prot:Q96H15
Source:KLH conjugated synthetic peptide derived from human TIM4:61-160/374
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. Studies have shown that TIM 4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM 1, and that this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM 4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM 4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM 1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Skeletal muscle (Mouse) Lysate at 40 ug
Primary: Anti-Hexokinase 2 (bs-10196R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 101 kD
Observed band size: 101 kD
Sample:
Lymph node (Mouse) Lysate at 40 ug
Testis (Mouse) Lysate at 40 ug
Primary: Anti-TIM4 (bs-22039R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
Sample:
Lymph node (Mouse) Lysate at 40 ug
Primary: Anti- TIM4 (bs-22039R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
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