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Anti-muscarinic Acetylcholine Receptor 1 antibody (bs-1150R)

Anti-muscarinic Acetylcholine Receptor 1 antibody (bs-1150R)

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Anti-muscarinic Acetylcholine Receptor 1 antibody

英文名称muscarinic Acetylcholine Receptor 1
中文名称毒蕈碱型乙酰胆碱受体M1抗体
别    名muscarinic acetylcholine receptor; M-AChR M1; Muscarinic Acetylcholine Receptor 1;cholinergic receptor, muscarinic 1; Chrm1; Chrm-1; M1; M1R; Muscarinic Acetylcholine receptor M1; Cholinergic receptor muscarinic 1; CHRM 1; CHRM1; HM 1; HM1; M1; M1 muscarinic cholinergic receptor; MGC30125; Muscarinic acetylcholine receptor M1; Acetylcholine receptor(M1).  

DATASHEET

Host:Rabbit

Target Protein:muscarinic Acetylcholine Receptor 1

IR:Immunogen Range:321-420/460

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:1128

Swiss Prot:P11229

Source:KLH conjugated synthetic peptide derived from human muscarinic Acetylcholine Receptor 1:321-420/460 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008].

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Cerebrum (Mouse) Lysate at 40 ug
Cerebrum (Rat) Lysate at 40 ug
HepG2(Human) Cell Lysate at 30 ug
Primary: Anti-muscarinic Acetylcholine Receptor 1 (bs-1150R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 51 kD
Observed band size: 61 kD

Sample:
Kidney(Rat) lysate at 30ug;
Brain(Rat) lysate at 30ug;
Primary: Anti-ChRM1/Acetylcholine receptor(M1) (bs-1150R) at 1:200 dilution;
Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 3000 dilution;
Predicted band size : 51kD
Observed band size : 51kD

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