Anti-HSD3B1 antibody
| 英文名称 | HSD3B1 |
| 中文名称 | 滋养层细胞抗原3β-HSD抗体 |
| 别 名 | 3 beta and steroid delta isomerase 1; 3 beta and steroid hydroJNC delta 5 steroid dehydrogenase; 3 beta HSD I; 3BH; 3BHSD; HGNC:5217; HSD3B; HSD3B1; HSDB3; HSDB3A; HydroJNC delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1; HydroJNC delta 5 steroid dehydrogenase; trophoblast antigen; 3BHS1_HUMAN; 3 beta-hydroJNCsteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3 beta-hydroJNCsteroid dehydrogenase/Delta 5-->4-isomerase type I; Short=3-beta-HSD I; Trophoblast antigen FDO161G; 3-beta-hydroJNC-Delta(5)-steroid dehydrogenase; 3-beta-hydroJNC-5-ene steroid dehydrogenase; Progesterone reductase; Steroid Delta-isomerase; Delta-5-3-ketosteroid isomerase. |
DATASHEET
Host:Rabbit
Target Protein:HSD3B1
IR:Immunogen Range:301-373/373
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3283
Swiss Prot:P14060
Source:KLH conjugated synthetic peptide derived from human HSD3B1:301-373/373
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroJNC steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroJNCsteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Paraformaldehyde-fixed, paraffin embedded (Rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HSD3B1) Polyclonal Antibody, Unconjugated (bs-3906R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HSD3B1) Polyclonal Antibody, Unconjugated (bs-3906R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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