Anti-IGFBP7 antibody
| 英文名称 | IGFBP7 |
| 中文名称 | 胰岛素样生长因子结合蛋白7抗体 |
| 别 名 | AGM; Angiomodulin; FSTL2; IBP-7; IBP7; IBP7_HUMAN; IGF binding protein 7; IGF-binding protein 7; IGFBP rP1; IGFBP-7; IGFBP-rP1; IGFBP7; IGFBPRP1; Insulin like growth factor binding protein 7; Insulin-like growth factor-binding protein 7; MAC25; MAC25 protein; PGI2 stimulating factor; PGI2-stimulating factor; Prostacyclin stimulating factor; Prostacyclin-stimulating factor; PSF; RAMSVPS; TAF; Tumor-derived adhesion factor. |
DATASHEET
Host:Rabbit
Target Protein:IGFBP7
IR:Immunogen Range:131-230/282
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3490
Swiss Prot:Q16270
Source:KLH conjugated synthetic peptide derived from human IGFBP7:131-230/282
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:IGF-BPs form high affinity complexes with both IGF-I and IGF-II and act to control of the distribution, function and activity of IGFs in various cell tissues and body fluids. There are seven named IGF-BPs. IGFBP7 plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. Additionally, IGFBP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle, and increased apoptosis. IGFBP7 is expressed in a wide range of normal human tissues and it usually shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Independently Validated Antibody, image provided by Science Direct, badge number 02663:Formalin-fixed and paraffin embedded human liver labeled with Anti-IGFBP7 Polyclonal Antibody, Unconjugated (bs-5098R) at 1:250 overnight at 25C followed by conjugation to the secondary antibody and DAB staining. Positive Control has great staining, however it may be nonspecific.
Independently Validated Antibody, image provided by Science Direct, badge number 02663:Formalin-fixed and paraffin embedded human kidney labeled with Anti-IGFBP7 Polyclonal Antibody, Unconjugated (bs-5098R) at 1:250 overnight at 25C followed by conjugation to the secondary antibody and DAB staining. Postive Control has great staining, however it may be nonspecific.
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