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Anti-phospho-GSK3 Beta (Tyr216) antibody (bs-4079R)

Anti-phospho-GSK3 Beta (Tyr216) antibody (bs-4079R)

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Anti-phospho-GSK3 Beta (Tyr216) antibody

英文名称phospho-GSK3 Beta (Tyr216)
中文名称磷酸化糖原合酶激酶3β抗体
别    名GSK3 beta (phospho Y216); p-GSK3 beta (phospho Y216);GSK3B(Phospho-Tyr216); GSK3B(Phospho-Y216); p-GSK-3 Beta(Tyr216); p-GSK-3 beta(Y216); Glycogen synthase kinase 3 beta; GSK 3 beta; GSK 3B; GSK3B; GSK3B protein; GSK3beta isoform; GSK3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; GSK3B_HUMAN.  

DATASHEET

Host:Rabbit

Target Protein:phospho-GSK3 Beta (Tyr216)

IR:Immunogen Range:VS(p-Y)IC

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:2932

Swiss Prot:P49841

Source:KLH conjugated Synthesised phosphopeptide derived from human GSK3 Beta around the phosphorylation site of Tyr216:VS(p-Y)IC 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Sheep
Guinea Pig
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
K562(Human) Cell Lysate at 30 ug
Primary: Anti-phospho-GSK3 Beta (Tyr216)  (bs-4079R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47/51 kD
Observed band size: 47/51 kD

Sample:
Testis (Mouse) Lysate at 40 ug
Thymus (Mouse) Lysate at 40 ug
NIH/3T3(Mouse) Cell Lysate at 30 ug
Primary: Anti-phospho-GSK3 Beta (Tyr216)  (bs-4079R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47/51 kD
Observed band size: 51 kD

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