Anti-phospho-TEM8 (Tyr382) antibody
| 英文名称 | phospho-TEM8 (Tyr382) |
| 中文名称 | 磷酸化肿瘤血管内皮标志物8抗体 |
| 别 名 | Anthrax toxin receptor 1; Anthrax toxin receptor 1 precursor; ANTXR 1; ANTXR1; ATR; TEM-8; TEM 8; TEM8; Tumor Endothelial Marker 8; Tumor endothelial marker 8 precursor; ANTR1_HUMAN; Anthrax toxin receptor-1; FLJ11298; FLJ21776. |
DATASHEET
Host:Rabbit
Target Protein:phospho-TEM8 (Tyr382)
IR:Immunogen Range:AS(p-Y)YG
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:84168
Swiss Prot:Q9H6X2
Source:KLH conjugated Synthesised phosphopeptide derived from human ANTXR1 around the phosphorylation site of Tyr382:AS(p-Y)YG
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Pig
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Bladder (Mouse) Lysate at 40 ug
Primary: Anti-phospho-TEM8 (Tyr382)( bs-5210R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 45 kD
Sample:
Uterus (Mouse) Lysate at 40 ug
Primary: Anti-phospho-TEM8 (Tyr382)( bs-5210R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 45 kD
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