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Anti-Phospho-NMDAR2B (Tyr1474) antibody (bs-8566R)

Anti-Phospho-NMDAR2B (Tyr1474) antibody (bs-8566R)

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Anti-Phospho-NMDAR2B (Tyr1474) antibody

英文名称Phospho-NMDAR2B (Tyr1474)
中文名称磷酸化谷氨酸受体2B抗体
别    名NMDAR2B (Phospho-Tyr1474); NMDAR2B (Phospho-Y1474); p-NMDAR2B (Tyr1474); p-NMDAR2B (Y1474); AW490526; Glutamate [NMDA] receptor subunit epsilon 2; Glutamate [NMDA] receptor subunit epsilon-2; Glutamate Receptor Ionotropic N Methyl D Aspartate 2B; Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B; Glutamate receptor ionotropic NMDA2B; Glutamate receptor subunit epsilon 2; Glutamate receptor, ionotropic, NMDA2B (epsilon 2); GRIN 2B; GRIN2B; hNR 3; hNR3; MGC142178; MGC142180; N methyl D asparate receptor channel subunit epsilon 2; N METHYL D ASPARTATE RECEPTOR CHANNEL SUBUNIT EPSILON 2; N methyl D aspartate receptor subtype 2B; N methyl D aspartate receptor subunit 2B; N methyl D aspartate receptor subunit 3; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NMDA NR2B; NMDA R2B; Nmdar2b; NMDE2; NMDE2_HUMAN; NME2; NR2B; NR3.  

DATASHEET

Host:Rabbit

Target Protein:Phospho-NMDAR2B (Tyr1474)

IR:Immunogen Range:HV(p-Y)EK

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:2904

Swiss Prot:Q13224

Source:KLH conjugated synthesised phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1252:HV(p-Y)EK 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008].

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
U251 (Human) Lysate at 30 ug
Primary: Anti-CREB-1 (bs-8566R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 163 kD
Observed band size: 163 kD

Sample:
U87-MG (Human) Lysate at 30 ug
Primary: Anti-CREB-1 (bs-8566R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 163 kD
Observed band size: 163 kD

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