Anti-KCNAB1/Kv beta 1 antibody
英文名称 | KCNAB1/Kv beta 1 |
中文名称 | 电压门控钾通道蛋白1抗体 |
别 名 | hKvb3; hKvBeta3; K(+) channel subunit beta-1; KCAB1_HUMAN; KCNA1B; KCNAB1; KV-BETA-1; Kvb1.3; Voltage-gated potassium channel beta-1 subunit; Voltage-gated potassium channel subunit beta-1. |
DATASHEET
Host:Rabbit
Target Protein:KCNAB1/Kv beta 1
IR:Immunogen Range:131-230/419
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7881
Swiss Prot:Q14722
Source:KLH conjugated synthetic peptide derived from human KCNAB1/Kv beta 1:131-230/419
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming ? subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV∫, also known as KCNAB1 (potassium voltage-gated channel, shaker-related subfamily, beta member 1), is a 419 amino acid accessory K+ channel protein that exists as three alternatively spliced isoforms and regulates the activity of the pore-forming ? subunit. It is expressed in brain, with highest levels detected in caudate nucleus, hippocampus and thalamus.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Heart (Rat) Lysate at 40 ug
Primary: Anti-KCNAB1’Kv beta 1 (bs-8691R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kD
Observed band size: 47 kD
Sample:
SH-SY5Y (Human) Cell Lysate at 30 ug
Primary: Anti-KCNAB1’Kv beta 1 (bs-8691R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kD
Observed band size: 47 kD
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