Anti-HAAO antibody (bs-11695R)

Anti-HAAO antibody

DATASHEET

Host:Rabbit

Target Protein:HAAO

IR:Immunogen Range:101-200/286

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:23498

Swiss Prot:P46952

Source:KLH conjugated synthetic peptide derived from human HAAO:101-200/286 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The 3-HAO family of proteins consists of intramolecular dioJNCgenases that contain non-heme ferrous iron. HAAO (3-hydroJNCanthranilate 3,4-dioJNCgenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe2+ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN), and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroJNCanthranilate to 2-amino-3-carboJNCmuconate semialdehyde. HAAO may play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Rabbit
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample: Liver (Mouse) Lysate at 40 ug
Primary: Anti-HAAO (bs-11695R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 33 kD
Observed band size: 33 kD

Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti- HAAO (bs-11695R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 33 kD
Observed band size: 30 kD