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Anti-phospho-LRRK2 (Thr1410) antibody (bs-11786R)

Anti-phospho-LRRK2 (Thr1410) antibody (bs-11786R)

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Anti-phospho-LRRK2 (Thr1410) antibody 

英文名称phospho-LRRK2 (Thr1410)
中文名称磷酸化富亮氨酸重复激酶2抗体
别    名LRRK2 (phospho T1410); LRRK2 (phospho Thr1410); p-LRRK2 (Thr1410); Dardarin; Leucine rich repeat kinase 2; LRRK 2; LRRK-2; LRRK2; PARK 8; PARK8; ROCO 2; ROCO-2; ROCO2; Leucine-rich repeat serine/threonine-protein kinase 2; Dardarin; LRRK2_HUMAN; augmented in rheumatoid arthritis 17; AURA17; Leucine rich repeat kinase 2; RIPK7.  

DATASHEET

Host:Rabbit

Target Protein:phospho-LRRK2 (Thr1410)

IR:Immunogen Range:FM(p-T)QR

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:120892

Swiss Prot:Q5S007

Source:KLH conjugated synthesised phosphopeptide derived from human LRRK2 around the phosphorylation site of Thr1410:FM(p-T)QR 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:LRRK2 (Dardarin) is encoded by the gene LRRK2. Genetic mutations of LRRK2 have been linked to Parkinsonism and synucleinopathies. LRRK2 belongs to the ROCO protein family and includes a protein kinase domain of the MAPKKK class and several other major functional domains.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (phospho-LRRK2 (Thr1410)) Polyclonal Antibody, Unconjugated (bs-11786R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (phospho-LRRK2 (Thr1410)) Polyclonal Antibody, Unconjugated (bs-11786R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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