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Anti-phospho-beta 2 Adrenergic Receptor (Ser355 + Ser356) antibody (bs-12979R)Anti-phospho-beta 2 Adrenergic Receptor (Ser355 + Ser356) antibody
英文名称 | phospho-beta 2 Adrenergic Receptor (Ser355 + Ser356) |
中文名称 | 磷酸化肾上腺素能受体β2/β2-AR抗体 |
别 名 | beta 2 Adrenergic Receptor (phospho S355 + S356); beta 2 Adrenergic Receptor (phospho S346); p-beta 2 Adrenergic Receptor (phospho S346); β2-adrenergic receptor; beta 2 Adrenergic Receptor; ADRB2; ADRB2R; ADRBR; ADRB2_HUMAN; Adrenergic beta 2 receptor surface; B2AR; BAR; beta 2 adrenoceptor; Beta 2 adrenoreceptor; BETA2AR; Catecholamine receptor; beta2-adrenergic receptor. |
DATASHEET
Host:Rabbit
Target Protein:phospho-beta 2 Adrenergic Receptor (Ser355 + Ser356)
IR:Immunogen Range:GY(p-S)(p-S)N
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:154
Swiss Prot:P07550
Source:KLH conjugated synthesised phosphopeptide derived from human beta 2 Adrenergic Receptor around the phosphorylation site of Ser355 + Ser356:GY(p-S)(p-S)N
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Beta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L type calcium channel Ca(V)1.2. This receptor channel complex also contains a G protein, an adenylyl cyclase, cAMP dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Lung (Mouse) Lysate at 40 ug
Primary: Anti-phospho-beta 2 Adrenergic Receptor (Ser355 + Ser356) (bs-12979R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD
Sample:
HepG2(Human) Cell Lysate at 30 ug
Primary: Anti-phospho-beta 2 Adrenergic Receptor (Ser355 + Ser356) (bs-12979R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD
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