Anti-DNA polymerase mu antibody
| 英文名称 | DNA polymerase mu |
| 中文名称 | DNA聚合酶μ/DNA pol μ抗体 |
| 别 名 | DNA Polymerase Mu; DNA-directed DNA polymerase mu; DNA-directed DNA/RNA polymerase mu; DPOLM_HUMAN; FLJ35482; Pol iota; Pol Mu; Polm; POLM protein; Polymerase (DNA directed) mu; Polymerase DNA directed mu; Tdt N; Tdt-N; TdtN; Terminal transferase. |
DATASHEET
Host:Rabbit
Target Protein:DNA polymerase mu
IR:Immunogen Range:261-360/494
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:27434
Swiss Prot:Q9NP87
Source:KLH conjugated synthetic peptide derived from human DNA polymerase mu:261-360/494
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoJNCnucleotideyltransferase. Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA polymerases, which show substrate specificity for deoJNCnucleotides, DNA Pol mu incorporates both deoJNCnucleotides and ribonucleotides in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample: Raji Cell(Human)Lysate at 30 ug
Primary: Anti-DNA polymerase mu (bs-13021R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55kD
Observed band size: 60kD
Sample:HepG2 Cell (Human) Lysate at 30 ug
Primary: Anti-DNA polymerase mu (bs-13021R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55kD
Observed band size: 60kD
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