Anti-CYP2C8 antibody
英文名称 | CYP2C8 |
中文名称 | 细胞色素P450 2C8抗体 |
别 名 | CP2C8_HUMAN; CPC8; CYP2C8; CYPIIC8; Cytochrome P450 2C8; Cytochrome P450 family 2 subfamily C polypeptide 8; Cytochrome P450 form 1; Cytochrome P450 IIC2; Cytochrome P450 MP-12; Cytochrome P450 MP-20; Cytochrome P450 subfamily IIC (mephenytoin 4 hydroJNClase) polypeptide 8; Flavoprotein linked monooJNCgenase; Microsomal monooJNCgenase; MP 12/MP 20; P450 form 1; P450 IIC2; P450 MP 12/MP 20; S mephenytoin 4 hydroJNClase; S-mephenytoin 4-hydroJNClase; Xenobiotic monooJNCgenase. |
DATASHEET
Host:Rabbit
Target Protein:CYP2C8
IR:Immunogen Range:51-150/490
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1558
Swiss Prot:P10632
Source:KLH conjugated synthetic peptide derived from human CYP2C8:51-150/490
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooJNCgenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoJNCcoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Rat
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
HepG2 Cell (Human) Lysate at 40 ug
Lovo Cell (Human) Lysate at 40 ug
Primary: Anti-CYP2C8(bs-14151R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 56kD
Observed band size: 56kD
Sample:
BRL-3A(Rat) Cell Lysate at 40 ug
Primary: Anti-CYP2C8 (bs-14151R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 56 kD
Observed band size: 56 kD
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