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Anti-ZDHHC13/HIP14L antibody (bs-18474R)

Anti-ZDHHC13/HIP14L antibody (bs-18474R)

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Anti-ZDHHC13/HIP14L antibody

英文名称ZDHHC13/HIP14L
中文名称ZDHHC13蛋白抗体
别    名DHHC 13; DHHC-13; FLJ10852; FLJ10941; HIP14 like; HIP14 related protein; HIP14-related protein; HIP14L; HIP3RP; Huntingtin interacting protein 14 related protein; Huntingtin interacting protein HIP3RP; Huntingtin-interacting protein 14-related protein; Huntingtin-interacting protein HIP3RP; Hypothetical protein similar to ankyrin repeat containing priotein AKR1; MGC64994; Palmitoyltransferase ZDHHC13; Probable palmitoyltransferase ZDHHC13; Putative MAPK activating protein PM03; Putative MAPK-activating protein PM03; Putative NF kappa B activating protein 209; Putative NF-kappa-B-activating protein 209; ZDH13_HUMAN; ZDHHC 13; ZDHHC13; Zinc finger DHHC domain containing 13; Zinc finger DHHC domain-containing protein 13.  

DATASHEET

Host:Rabbit

Target Protein:ZDHHC13/HIP14L

IR:Immunogen Range:501-600/622

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:54503

Swiss Prot:Q8IUH4

Source:KLH conjugated synthetic peptide derived from human ZDHHC13/HIP14L:501-600/622 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:ZDHHC13 is a 622 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and six ANK repeats. Expressed as multiple alternatively spliced isoforms, HIP14L functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and a protein-cyeteine to an S-palmitoyl protein and CoA and, via this catalytic activity, may be involved in the NFⅹB signaling pathway. The gene encoding HIP14L maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Paraformaldehyde-fixed, paraffin embedded (human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZDHHC13) Polyclonal Antibody, Unconjugated (bs-18474R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

Paraformaldehyde-fixed, paraffin embedded (rat stomach tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZDHHC13) Polyclonal Antibody, Unconjugated (bs-18474R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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