Anti-PRCC/Papillary renal cell carcinoma antibody
| 英文名称 | PRCC/Papillary renal cell carcinoma |
| 中文名称 | 头状肾细胞癌PRCC抗体 |
| 别 名 | Papillary renal cell carcinoma (Translocation associated), isoform CRA_b; Papillary renal cell carcinoma translocation-associated gene protein; PRCC; PRCC_HUMAN; Proline rich protein PRCC; Proline-rich protein PRCC; RCCP1; TPRC. |
DATASHEET
Host:Rabbit
Target Protein:PRCC/Papillary renal cell carcinoma
IR:Immunogen Range:401-491/491
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5546
Swiss Prot:Q92733
Source:KLH conjugated synthetic peptide derived from human PRCC/Papillary renal cell carcinoma:401-491/491
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
293T(Human) Cell Lysate at 30 ug
Primary: Anti-PRCC (bs-21077R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PRCC/Papillary renal cell carcinoma) Polyclonal Antibody, Unconjugated (bs-21077R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
好评度