Anti-IL-1 Beta antibody (bs-20449R)

Anti-IL-1 Beta antibody 

DATASHEET

Host:Rabbit

Target Protein:IL-1 Beta

IR:Immunogen Range:181-269/269

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:3553

Swiss Prot:P01584

Source:KLH conjugated synthetic peptide derived from human IL-1 Beta:181-269/269 

Purification:affinity purified by Protein A

Storage:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooJNCgenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Bee
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Hemocyte (Mouse) Lysate at 40 ug
Primary: Anti-IL-1 Beta (bs-20449R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 17 kD
Observed band size: 30 kD

Sample: Kidney (Mouse) Lysate at 40 ug
Primary: Anti-IL-1 Beta (bs-20449R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 17kD
Observed band size: 16kD