Anti-Phospho-Paxillin (Tyr118) antibody
| 英文名称 | Phospho-Paxillin (Tyr118) |
| 中文名称 | 磷酸化桩蛋白Paxillin抗体 |
| 别 名 | p-paxillin; p-PXN(Y118); p-PXN(Tyr118); Paxillin (phospho Y118); Paxillin (phospho Tyr118); p-Paxillin (Tyr118); Paired box protein Pax 1; PAX 1; PAX1; Paxillin alpha; PXN; PXN protein; FLJ16691; FLJ23042; FLJ16691; PAXI_HUMAN; Paxillin; PXN protein. |
DATASHEET
Host:Rabbit
Target Protein:Phospho-Paxillin (Tyr118)
IR:Immunogen Range:HV(p-Y)SF
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5829
Swiss Prot:P49023
Source:KLH conjugated Synthesised phosphopeptide derived from human Paxillin around the phosphorylation site of Tyr118:HV(p-Y)SF
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Hela(Human) Cell Lysate at 30 ug
MCF-7(Human) Cell Lysate at 30 ug
NIH/3T3(Mouse) Cell Lysate at 30 ug
A549(Human) Cell Lysate at 30 ug
Primary: Anti- Phospho-Paxillin (Tyr118) (bs-3352R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 68 kD
Observed band size: 60 kD
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