Anti-phospho-DOK1 (Tyr398) antibody
| 英文名称 | phospho-DOK1 (Tyr398) |
| 中文名称 | 磷酸化D酪氨酸激酶衰减蛋白1抗体 |
| 别 名 | DOK1 (phospho Y398); DOK1 (phospho Tyr398); p-DOK1 (phospho Y398); docking protein 1 (downstream of tyrosine kinase 1); Docking protein 1 (p62(dok)) (Downstream of tyrosine kinase 1) (pp62).; docking protein 1 62kD (downstream of tyrosine kinase 1); Docking protein 1 62kD; Docking protein 1 62kD; Docking protein 1; DOK 1; DOK1; DOK-1; DOK1_HUMAN; Downstream of tyrosine kinase 1; p62(dok); P62DOK; pp62; pp62. |
DATASHEET
Host:Rabbit
Target Protein:phospho-DOK1 (Tyr398)
IR:Immunogen Range:EG(-Y)EL
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1796
Swiss Prot:Q99704
Source:KLH conjugated Synthesised phosphopeptide derived from human DOK1 around the phosphorylation site of Tyr398:EG(-Y)EL
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
Spleen (Mouse) Lysate at 40 ug
Lymph node (Mouse) Lysate at 40 ug
Primary: Anti- phospho-DOK1 (Tyr398) (bs-5290R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 52 kD
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