Anti-Phospho-PDGFRA (Tyr762) antibody
| 英文名称 | Phospho-PDGFRA (Tyr762) |
| 中文名称 | 磷酸化血小板源性生长因子受体α |
| 别 名 | PDGFRA(phospho Y762); PDGF Receptor alpha(Tyr849)/PDGF Receptor beta (Tyr857); Platelet–dirived growth factor receptor-alpha; Alpha platelet derived growth factor receptor; CD 140a; CD140a; CD140a antigen; MGC74795; PDGF alpha chain; PDGF R alpha; PDGFR 2; PDGFR A; PDGFR alpha; PDGFR2; PDGFRA; Platelet derived growth factor receptor 2; Platelet derived growth factor receptor alpha; Platelet derived growth factor receptor alpha polypeptide; PGFRA_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:Phospho-PDGFRA (Tyr762)
IR:Immunogen Range:SL(p-Y)DR
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5156
Swiss Prot:P16234
Source:KLH conjugated Synthesised phosphopeptide derived from human PDGFRA around the phosphorylation site of Tyr762:SL(p-Y)DR
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The PDGF Receptor Type A (Alpha platelet-derived growth factor receptor precursor, CD140a antigen), a 170kD protein, binds all three isoforms of PDGF with high affinity whereas the PDGF Receptor Type B, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity. Both receptors are transmembranous, ligand activated protein tyrosine kinases, which phosphorylate a number of important signal transduction proteins, which are bound with differential affinities via SH2 domains. The response of any given cell to PDGF will depend on the types of receptors displayed on the surface and isoforms of PDGF present in the extracellular environment.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
HepG2(Human) Cell Lysate at 30 ug
Primary: Anti- Phospho-PDGFRA (Tyr762) (bs-5534R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 170 kD
Observed band size: 170 kD
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