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Anti-phospho-Kv2.1 (Tyr128) antibody (bs-5535R)

Anti-phospho-Kv2.1 (Tyr128) antibody (bs-5535R)

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Anti-phospho-Kv2.1 (Tyr128) antibody

英文名称phospho-Kv2.1 (Tyr128)
中文名称磷酸化钾通道蛋白DRK1抗体
别    名Kv2.1 (phospho Y128); p-Kv2.1 (phospho Y128); Kv2.1(phospho Tyr128); Delayed rectifier potassium channel 1; Delayed rectifier potassium channel Kv2.1; DRK 1; DRK1; h DRK1 K(+) channel; h-DRK1; hDRK 1; hDRK1; KCB 1; KCB1; KCNB1; KCNB1_HUMAN; KV2.1; Potassium channel protein DRK1; Potassium voltage gated channel shab related subfamily member 1; Potassium voltage-gated channel subfamily B member 1; Voltage-gated potassium channel subunit Kv2.1.  

DATASHEET

Host:Rabbit

Target Protein:phospho-Kv2.1 (Tyr128)

IR:Immunogen Range:DEI(p-Y)LE

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:3745

Swiss Prot:Q14721

Source:KLH conjugated Synthesised phosphopeptide derived from human Kv21 around the phosphorylation site of Tyr128:DEI(p-Y)LE 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq].

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Tissue/cell: Rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Kv2’1 Polyclonal Antibody, Unconjugated(bs-5535R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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