Anti-Sin3b antibody
英文名称 | Sin3b |
中文名称 | 转录抑制蛋白Sin3b抗体 |
别 名 | SIN3 homolog B transcription regulator; Transcriptional corepressor Sin3b; SIN3B_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:Sin3b
IR:Immunogen Range:261-360/1162
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:23309
Swiss Prot:O75182
Source:KLH conjugated synthetic peptide derived from human Sin3b:261-360/1162
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample:
293T(Human) Cell Lysate at 30 ug
Primary: Anti- Sin3b (bs-4215R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 133 kD
Observed band size: 133 kD
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