Anti-Caspase-7 p11 antibody (bs-2322R)

Anti-Caspase-7 p11 antibody 

DATASHEET

Host:Rabbit

Target Protein:Caspase-7 p11

IR:Immunogen Range:211-303/303

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:840

Swiss Prot:P55210

Source:KLH conjugated synthetic peptide derived from human caspase-7 isoform alpha subunit p11:211-303/303 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq].

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Images provided the Independent Validation Program (badge number 029653)Formalin-fixed and paraffin embedded human prostate labeled with Rabbit Anti-Caspase-7 Polyclonal Antibody (bs-2322R) at 1:250 overnight at room temperature followed by conjugation to secondary antibody.