Anti-PDGF-D/SCDGFB antibody (bs-5776R)

Anti-PDGF-D/SCDGFB antibody 

DATASHEET

Host:Rabbit

Target Protein:PDGF-D/SCDGFB

IR:Immunogen Range:271-370/370

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:80310

Swiss Prot:Q9GZP0

Source:KLH conjugated synthetic peptide derived from human SCDGFB:271-370/370 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:SCDGFB (Spinal cord derived growth factor B) is a member of the platelet derived growth factor family. It only forms homodimers and does not dimerize with the other three family members. It is a potent mitogen for cells of mesenchymal origin. It is activated by proteolytic cleavage and this active form acts as a specific ligand for beta platelet derived growth factor receptor. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. It induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:
Control (-) Cell Lysate at 8 ug Human PDGF-D (Full Length) Overexpression Cell Lysate at 8ug Primary: Anti-PDGF-D (bs-5776R) at 1/2000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 14/41 kD
Observed band size: 41 kD