Anti-Dermokine beta antibody
| 英文名称 | Dermokine beta |
| 中文名称 | Dermokine β蛋白抗体 |
| 别 名 | Dermokineβ; Dermokine-β; DMKN;Dermokine beta; Dermokine delta 1; Dermokine delta 5a; Dermokine delta 5b; Dermokine gamma 1; Dermokine gamma 2; UNQ729; ZD52F10 protein; Epidermis-specific secreted protein SK30/SK89; DMKN_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:Dermokine beta
IR:Immunogen Range:401-476/476
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:93099
Swiss Prot:Q6E0U4
Source:KLH conjugated synthetic peptide derived from human Dermokine beta:401-476/476
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Dermokine, also known as DMKN, ZD52F10 or UNQ729, is a 476 amino acid secreted protein that belongs to the dermokine family and exists as 15 alternatively spliced isoforms, the most notable of which are designated ? and ∫. Existing as a homooligomer that can either homodimerize or homotrimerize, Dermokine is expressed in the epidermis, as well as in the epithelia of the lung and small intestine where it is thought to function as a regulator of keratinocyte differentiation, possibly playing a role in inflammatory responses. The gene encoding Dermokine maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:50-200)
Cross Reactive Species:Human
Rat
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Tissue/cell: rat small intestine tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Dermokine beta Polyclonal Antibody, Unconjugated(bs-9056R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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