Anti-E3 ubiquitin ligase antibody
| 英文名称 | E3 ubiquitin ligase |
| 中文名称 | E3泛素连接酶抗体 |
| 别 名 | C1orf166; E3 ubiquitin ligase; E3 ubiquitin protein ligase MUL1; FLJ12875; GIDE; Growth inhibition and death E3 ligase; MAPL; Mitochondrial anchored protein ligase; Mitochondrial ubiquitin ligase activator of NFKB 1; MUL1; MULAN; Putative NF kappa B activating protein 266; RING finger protein 218; RNF218; RP23-25C1.10-002. |
DATASHEET
Host:Rabbit
Target Protein:E3 ubiquitin ligase
IR:Immunogen Range:51-150/352
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:79594
Swiss Prot:Q969V5
Source:KLH conjugated synthetic peptide derived from human E3 ubiquitin ligase/RNF218:51-150/352
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Rabbit
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Sample: Heart (Mouse) Lysate at 40 ug
Primary: Anti- E3 ubiquitin ligase (bs-9663R) at 1/300 dilution
Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/5000 dilution
Predicted band size: 40 kD
Observed band size: 40 kD
好评度