Anti-DOK5 antibody (bs-8587R)

Anti-DOK5 antibody

DATASHEET

Host:Rabbit

Target Protein:DOK5

IR:Immunogen Range:21-120/306

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:55816

Swiss Prot:Q9P104

Source:KLH conjugated synthetic peptide derived from human DOK5/IRS6:21-120/306 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The downstream of kinase family (Dok-1-7) are members of a class of “docking” proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4 and Dok-5 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to Insulin and Insulin-like growth factor-1. The gene encoding human Dok-5 maps to chromosomal location 20q13.2.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
Flow-Cyt(5μg/Test)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

The blue histogram is unstained cells(HepG 2).
The Wathet Blue histogram is cells stained with secondary antibody alone.The Orange histogram is cells stained with rabbit IgG isotype control antibody plus secondary antibody.
The green histogram is cells stained with Rabbit Anti-DOK5 antibody (bs-8587R) plus secondary antibody.5μg in 100μL 1 X PBS containing 0.5% BSA.