Anti-PCDHA11 antibody (bs-11124R)

Anti-PCDHA11 antibody

DATASHEET

Host:Rabbit

Target Protein:PCDHA11

IR:Immunogen Range:351-450/949

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:56138

Swiss Prot:Q9Y5I1

Source:KLH conjugated synthetic peptide derived from human PCDHA11:351-450/949 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin (PCDH) gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protein products of PCDH-alpha genes interact with Integrin ∫1 to promote cell adhesion and form oligomers with PCDH-gamma proteins at specific membrane sites. PCDHA11 is a 949 amino acid single-pass transmembrane protein that contains six cadherin domains and functions as a potential calcium-dependent cell-adhesion protein, possibly playing a role in the creation and maintenance of neuronal connections. There are two isoforms of PCDHA11 that are produced as a result of alternative splicing events.

Size:100ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Sample:Rsc96 Cell (Rat)Cell Lysate at 40 ug
Primary: Anti-PCDHA11(bs-11124R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 100kD
Observed band size: 110kD