Anti-KIF1A antibody
| 英文名称 | KIF1A |
| 中文名称 | 微管驱动蛋白家族成员1A抗体 |
| 别 名 | ATSV; Axonal transporter of synaptic vesicles; C2orf20; hUnc 104; hUnc-104; hunc104; Kif1a; KIF1A related protein; KIF1A_HUMAN; kinesin like protein; kinesin like protein KIF1A; Kinesin-like protein KIF1A; Microtubule based motor; Microtubule based motor KIF1A; Microtubule-based motor KIF1A; Unc 104 and KIF1A related protein; Unc 104; Unc-104- and KIF1A-related protein. |
DATASHEET
Host:Rabbit
Target Protein:KIF1A
IR:Immunogen Range:1-100/1690
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:547
Swiss Prot:Q12756
Source:KLH conjugated synthetic peptide derived from human KIF1A:1-100/1690
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1C is a member of the KIF1/Unc104 family of kinesin-like proteins, which are involved in the transport of mitochondria or synaptic vesicles in axons. The human KIF1A gene encodes a neuron-specific motor protein that delivers synaptic vesicle precursors to nerve terminals. KIF1A is a monomeric, globular molecule and has rapid anterograde motor activity (1.2 microns/s). KIF1A-mediated axonal transport plays a critical role in viability, maintenance and function of neurons, particularly mature neurons. KIF1A is associated with organelles that contain synaptic vesicle proteins such as synaptotagmin, synaptophysin and Rab 3A.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (KIF1A) Polyclonal Antibody, Unconjugated (bs-11350R) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP)and DAB staining.
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