Anti-SH3GL3 antibody
英文名称 | SH3GL3 |
中文名称 | 胞浆蛋白SH3GL3抗体 |
别 名 | Endophilin I-III; Endophilin-III; CNSA3; EEN 2B L3; EEN B2; EEN2BL3; EENB2; Endophilin 3; Endophilin A3; H.sapiens mRNA for protein containing SH3 domain, SH3GL3; HsT19371; SH3 domain containing GRB2 like protein 3; SH3 domain GRB2 like 3; SH3 domain protein 2C; SH3D2C; SH3P13; SH3G3_HUMAN. |
DATASHEET
Host:Rabbit
Target Protein:SH3GL3
IR:Immunogen Range:121-220/347
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6457
Swiss Prot:Q99963
Source:KLH conjugated synthetic peptide derived from human SH3GL3:121-220/347
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I, II and III, or alternatively known as SH3P4, SH3P8 and SH3P13, respectively. These proteins associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the endophilins are consistent with their cellular functions at the neuronal synapse, as Endophilin I is ex- pressed only in the brain. Both Endophilin II and Endophilin III are detected in a variety of tissues. Endophilin I is also implicated in modulating G protein-coupled receptor signaling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery.
Size:100ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Rabbit
Sheep
.
For research use only. Not intended for diagnostic or therapeutic use.
VALIDATION IMAGES
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SH3GL3) Polyclonal Antibody, Unconjugated (bs-11702R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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