Anti-DOCK7 antibody (bs-11825R)

Anti-DOCK7 antibody

DATASHEET

Host:Rabbit

Target Protein:DOCK7

IR:Immunogen Range:1401-1500/2140

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:85440

Swiss Prot:Q96N67

Source:KLH conjugated synthetic peptide derived from human DOCK7:1401-1500/2140 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:DOCK 7 is a 2,140 amino acid protein that localizes to developing axons and contains one DHR-1 domain and one DHR-2 domain. Expressed in a variety of tissues, DOCK 7 functions as a guanine nucleotide exchange factor (GEF) that specifically activates Rac 1 and Rac 3 by catalyzing the exchange of bound GDP for free GTP. Multiple isoforms of DOCK 7 exist due to alternative splicing events.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Horse
Rabbit
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DOCK7) Polyclonal Antibody, Unconjugated (bs-11825R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.