Anti-GPRC5B antibody (bs-12029R)

Anti-GPRC5B antibody

DATASHEET

Host:Rabbit

Target Protein:GPRC5B

IR:Immunogen Range:1-100/403

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:51704

Swiss Prot:Q9NZH0

Source:KLH conjugated synthetic peptide derived from human G protein coupled receptor family C group 1 member B:1-100/403 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:GPRC5B (G protein-coupled receptor family C group 5 member B, retinoic acid-induced gene 2 protein) is a 403 amino acid protein encoded by the human GPRC5B gene. GPRC5B is an orphan receptor member of the G protein-coupled receptor 3 family. G protein-coupled receptors (GPCRs or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. Key roles for G protein-coupled receptors include control of protein maturation and cell surface delivery, and providing the correct framework for interactions with both heterotrimeric G proteins and arrestins to allow signal generation and termination. This retinoic acid-inducible G protein-coupled receptor provides evidence for a possible interaction between retinoid and G protein signaling pathways. GPRC5B is highly expressed in kidney, pancreas and testis, and has moderate expression in brain, heart, prostate, small intestine and spleen.

Size:100ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg/Test)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
Sheep
.

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Positive control: (mo)Splenocytes(2% Paraformaldehyde-fixed )
Isotype Control Antibody: Rabbit IgG; Dilution: 1μg in 100 μl 1 X PBS containing 0.5% BSA
Secondary Antibody: Goat anti-rabbit IgG-FITC; Dilution: 1:200 in 1 X PBS containing 0.5% BSA
Primary Antibody: rabbit Anti-GPRC5B (bs-12029R); Dilution: 1μg in 100 μl 1X PBS containing 0.5% BSA